SIRT1 is involved in different physiological functions including DNA repair, genomic stability, apoptosis, antioxidant effect, and enhancement of mitochondrial biogenesis (Yanagisawa et al
Eyeliss (hesperidin methyl chalcone, dipeptide-2, and palmitoyl tetrapeptide-7 combination) specifically targets fluid retention dark circles through improving lymphatic drainage removing accumulated fluids, reducing capillary permeability decreasing fluid leakage into surrounding tissues, and anti-inflammatory effects minimizing puffiness-related darkness
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Additionally, aging also alters the immune system, which is subsequently leading to inflammaging